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Bullous pemphigoid

Bullous pemphigoid is an autoimmune skin disease usually affecting the older population. An individual's own immune system mistakenly makes antibodies against certain components of their own skin causing itchy blisters to appear on the scalp, trunk, arms, and legs. It can also infrequently affect the mucous membranes (i.e. eyes and mouth). It may be localized to one area or be widespread and severity can vary among patients. Diagnosis is often made by a skin biopsy that is sent for pathology review and immunofluorescence. Treatment depends on severity of disease.